| Study identified Ski as a functional tumor suppressor with frequent epigenetic inactivation in lung cancer. | lung, |
| The cancer-associated Sm-like oncogene: a novel target for the gene therapy of pancreatic cancer. | pancreatic, |
| Overexpression of the Sm-like proto-oncogene in primary and metastatic pancreatic endocrine tumors. | pancreatic, |
| I discuss the basis for repression of intracellular TGF-beta signaling by SKI, some additional activities of this protein, and propose that by disrupting multiple tumor suppressor pathways, SKI functions as a melanoma oncogene. | skin, |
| Repression of TGF-beta signaling by the oncogenic protein SKI in human melanomas: consequences for proliferation, survival, and metastasis. | skin, |
| Expression of the nuclear oncogene Ski in patients with acute myeloid leukemia treated with all-trans retinoic acid. | leukemia, |
| Results indicate that SKI exploits multiple regulatory levels of the TGF-beta pathway and its deficiency restores TGF-beta tumor suppressor and apoptotic activities in spite of the likely presence of oncogenic mutations in melanoma tumors. | skin, |
| A two-gene signature, SKI and SLAMF1, predicts time-to-treatment in previously untreated patients with chronic lymphocytic leukemia. | leukemia, |
| Two genes were consistently retained in the models with clinical variables: SKI (v-SKI avian sarcoma viral oncogene homolog) and SLAMF1 (signaling lymphocytic activation molecule family member 1; CD150). | sarcoma, |
| Gene expression profiling to define the cell intrinsic role of the SKI proto-oncogene in hematopoiesis and myeloid neoplasms. | neoplasm, |
| Expression of the c-ski proto-oncogene in human melanoma cell lines. | skin, |
| The Ski oncoprotein interacts with the Smad proteins to repress TGFbeta signaling. | None |
| Interaction of the Ski oncoprotein with Smad3 regulates TGF-beta signaling. | None |
| Loss of the SKI proto-oncogene in individuals affected with 1p36 deletion syndrome is predicted by strain-dependent defects in Ski-/- mice. | None |
| c-Jun associates with the oncoprotein Ski and suppresses Smad2 transcriptional activity. | None |
| An Alw 26I PCR-RFLP in exon 1 of the porcine SKI oncogene and mapping the gene to the RYR1 ( CRC ) linkage group on chromosome 6. | None |
| Structural mechanism of Smad4 recognition by the nuclear oncoprotein Ski: insights on Ski-mediated repression of TGF-beta signaling. | None |
| Signal-dependent N-CoR requirement for repression by the Ski oncoprotein. | None |
| The oncoprotein Ski acts as an antagonist of transforming growth factor-beta signaling by suppressing Smad2 phosphorylation. | None |
| Negative regulation of BMP signaling by the ski oncoprotein. | None |