| SOX4 acts as a tumor suppressor in glioblastoma multiforme cells by inducing cell cycle arrest and inhibiting cell growth | glioblastoma, |
| Stable transfection of SOX4 into nontransformed prostate cells enabled colony formation in soft agar, suggesting that, in the proper cellular context, SOX4 can be a transforming oncogene. | colorectal,prostate, |
| Sex-determining region Y box 4 is a transforming oncogene in human prostate cancer cells. | prostate, |
| In lung cancer, SOX4 is overexpressed due to gene amplification and provide evidence of oncogenic properties of SOX4. | lung, |
| Epigenetic repression of microRNA-129-2 leads to overexpression of SOX4 oncogene in endometrial cancer. | endometrial, |
| Methylation-mediated repression of microRNA 129-2 enhances oncogenic SOX4 expression in hepatocellular carcinoma. | liver, |
| Sox4 is a key oncogenic target in C/EBPalpha mutant acute myeloid leukemia. | leukemia, |
| we identified that SOX4 was oncogenic in chondrosarcoma and negatively regulated by miR-30a in vitro. | sarcoma, |
| SOX4 may contribute to oncogenic phenotypes of head and neck squamous cell carcinoma cells by promoting cell survival and causing chemoradioresistance. It could be a potential prognostic marker for oral squamous cell carcinoma . | HNSC, |
| microRNA-449 family acts as a tumor suppressor in liver cancer by causing cell death and inhibiting cell migration. These effects are caused by downregulation of the oncogene SOX4. | liver, |
| SOX4 appears to be an important tumor oncogene in the regulation of osteosarcoma cell proliferation, apoptosis, and invasion | osteosarcoma, |
| SOX4, a previously reported oncogenic transcriptional factor and modulator of epithelial-mesenchymal transition, is a direct target gene of miR30a. | None |