Sentence and cancer type
Showing 121-140 of 213 items.
SentenceCancertype
Activation of the proto-oncogene p60c-src by point mutations in the SH2 domain. None
Myristoylated src-oncogene products are potently detected by the monoclonal antibody to the NH2-terminal myristoyl-Gly-Ser-Ser-Lys src-peptide. None
Depletion of insulin receptor substrate 2 reverses oncogenic transformation induced by v-src. None
These findings demonstrate the effectiveness of simultaneous targeting of Src and the downstream signaling partners Stat3 and/or cMyc to inhibit the growth and oncogenic properties of a human cancer cell line.None
The src oncogene can regulate a human glucose transporter expressed in chicken embryo fibroblasts. None
Tumor-suppressor role for the SPOP ubiquitin ligase in signal-dependent proteolysis of the oncogenic co-activator SRC-3/AIB1. None
The oncogenic protein p60v-src has competence activity but does not activate phosphatidylinositol turnover or protein kinase C in Balb/c 3T3 cells. None
Constitutive phosphorylation of the receptor for insulinlike growth factor I in cells transformed by the src oncogene. None
Functional expression of dihydropyridine-insensitive calcium channels during PC12 cell differentiation by nerve growth factor (NGF), oncogenic ras, or src tyrosine kinase. None
p120RasGAP-mediated activation of c-Src is critical for oncogenic Ras to induce tumor invasion. None
The proto-oncogene c-src is involved in primordial follicle activation through the PI3K, PKC and MAPK signaling pathways. None
Mind the gap; regulation of gap junctional, intercellular communication by the SRC oncogene product and its effectors. None
Activation of Src, Fyn and Yes non-receptor tyrosine kinases in keratinocytes expressing human papillomavirus (HPV) type 16 E7 oncoprotein. None
Drosophila PRL-1 is a growth inhibitor that counteracts the function of the Src oncogene. None
Drosophila actin-Capping Protein limits JNK activation by the Src proto-oncogene. None
This study uncovers a novel mechanism where a phosphoinositide-synthesizing enzyme, PIPKIgammai2, functions with the proto-oncogene Src, to regulate oncogenic signaling.None
Phosphatidylinositol phosphate 5-kinase Igammai2 in association with Src controls anchorage-independent growth of tumor cells. None
pp60c-src encoded by the proto-oncogene c-src is a product of sensory neurons. None
Members of the src and ras oncogene families supplant the epidermal growth factor requirement of BALB/MK-2 keratinocytes and induce distinct alterations in their terminal differentiation program. None
Src-like-adaptor protein (SLAP) differentially regulates normal and oncogenic c-Kit signaling. None