| data indicate that the cell cycle-dependent pattern of BRCA1 tumor suppressor expression is determined in part by ubiquitin-dependent proteasomal degradation | None |
| BRCA1 affects lipogenesis through binding to P-ACCA, suggesting a new mechanism by which BRCA1 may exert a tumor suppressor function | None |
| BRCA1 modulates protein synthesis via its interaction with PABP, providing a novel mechanism by which BRCA1 may exert its tumor suppressor function | None |
| Role for BRCA1 in modulating estrogen biosynthesis in Adipose stem cells, contributing to its tissue-specific tumor suppressor function. | None |
| distinct single nucleotide changes in the BRCT domain of BRCA1 affect binding of this protein to the tumor suppressor p53 | None |
| roles for BRCA1 in both mammary gland development and in tumor suppression against mutagen-induced mammary gland neoplasia | None |
| The tumor suppressor BRCA1 tandem C-terminal BRCT2 and BRCT3 domains of Mcph1 are necessary for the formation of ionizing radiation-induced nuclear foci, while the N-terminal BRCT1 is required for centrosomal localization in irradiated cells. | None |
| MTA1-mediated transcriptional repression of BRCA1 tumor suppressor gene. | None |
| The unconventional export of proteins such as RHAMM is a novel process that modifies the roles of tumor suppressors and promoters, such as BRCA1 and CD44, and might provide new targets for therapeutic intervention. | None |
| The remarkable similarities between the mammary carcinomas of Bard1-, Brca1-, and Bard1/Brca1-mutant mice indicate that the tumor suppressor activities of both genes are mediated through the BRCA1/BARD1 heterodimer. | None |
| Pubertal physical activity up-regulates tumor suppressor genes BRCA1, p53 and ER-beta, and reduced ER-alpha/ER-beta ratio in the mammary gland | None |
| CpG island tumor suppressor promoter methylation in non-BRCA-associated early mammary carcinogenesis. | None |
| Study established a robust assay system to analyze the function of BRCA1 in regulating homologous recombination, which is critical for its tumor suppressor function. | None |
| The UBXN1 protein associates with autoubiquitinated forms of the BRCA1 tumor suppressor and inhibits its enzymatic function. | None |
| This feature item briefly reviews the relation of the tumor suppressor function of BRCA1 with DNA damage and repair. | None |
| Methylation of the tumor suppressor protein, BRCA1, influences its transcriptional cofactor function. | None |
| BRCA1 modulates the expression of hnRNPA2B1 and KHSRP involved in the processing of RNA, highlighting the complex nature of BRCA1-associated tumor suppressor function and disclosing a novel mechanism by which BRCA1 may affect transcription. | None |
| These results support the existence of a heterozygous phenotype of BRCA1 and suggest that the loss of one BRCA1 allele may suppress the fitness advantage caused by the inactivation of other tumor suppressor genes. | None |
| role of BRCA1 in tumor suppression and DNA damage response, including DNA damage-induced cell cycle checkpoint activation and DNA damage repair is discussed. | None |
| Regulated recruitment of tumor suppressor BRCA1 to the p21 gene by coactivator methylation. | None |