| Study shows that Aurora-A acts as a tumor suppressor by suppressing neuroblast self-renewal and promoting neuronal differentiation. | None |
| Overexpression of oncogenic STK15/BTAK/Aurora A kinase in human pancreatic cancer. | pancreatic, |
| Overexpression of Aurora-A contributes to malignant development of human esophageal squamous cell carcinoma. | esophageal, |
| ZNF217 confers resistance to the pro-apoptotic signals of paclitaxel and aberrant expression of Aurora-A in breast cancer cells. | breast, |
| Protein tyrosine phosphatase receptor delta acts as a neuroblastoma tumor suppressor by destabilizing the aurora kinase A oncogene. | neuroblastoma, |
| Chromosomal instability is induced by overexpression of the oncogene AURKA or by loss of the tumour suppressor gene CHK2, a genetic constitution found in colorectal cancers. | colorectal, |
| Increased microtubule assembly rates influence chromosomal instability in colorectal cancer cells. | colorectal, |
| aberrantly methylated AURKA and Fos proto-oncogene may be potential therapeutic targets for hepatitis C viruspositive hepatocellular carcinoma. | liver, |
| The suppression of STK15 oncogenic activity by p53 might be explained by the finding that p53 inhibited STK15 kinase activity via direct interaction with the latter_s Aurora box. This revealed a novel mechanism for the tumor suppressor function of p53. | None |
| Aurora-A gene amplification and overexpression play a role in human carcinogenesis, largely due to the effect of Aurora-A on oncogenic cell growth, rather than a loss of maintenance of centrosomal or chromosomal integrity | None |
| Here, we show that interactions between the prometastatic scaffolding protein HEF1/Cas-L/NEDD9 and the oncogenic Aurora A (AurA) kinase at the basal body of cilia causes phosphorylation and activation of HDAC6, promoting ciliary disassembly. | None |
| ASAP is a novel substrate of the oncogenic mitotic kinase Aurora-A: phosphorylation on Ser625 is essential to spindle formation and mitosis. | None |
| The Aurora-A/TPX2 complex: a novel oncogenic holoenzyme?. | None |
| association of Aurora-A and TPX2 gives rise to a novel functional unit with oncogenic properties.[review] | None |
| inhibition of two oncogenic pathways (AURKA and NOTCH-1) by small-molecular inhibitors induced significant growth arrest in NK-cell lines | None |