Sentence and cancer type
Showing 1-7 of 7 items.
SentenceCancertype
TAZ functions as a tumor suppressor in multiple myeloma by downregulating MYCNone
The ciliopathy disease protein NPHP9 promotes nuclear delivery and activation of the oncogenic transcriptional regulator TAZ. liver,
TEADs mediate nuclear retention of TAZ to promote oncogenic transformation. None
WW domain-mediated interaction with Wbp2 is important for the oncogenic property of TAZ. None
Vgll1 interacts with TEAD4 in a manner similar to the transcription coactivators, as well as oncogenes YAP and TAZ, despite having a varied primary sequence. Vgll1 has the potential to promote cancer progression.None
Structural and functional similarity between the Vgll1-TEAD and the YAP-TEAD complexes. None
Genome-wide association between YAP/TAZ/TEAD and AP-1 at enhancers drives oncogenic growth. None