Sentence and cancer type
Showing 1-9 of 9 items.
SentenceCancertype
Involvement of the TCF3 gene in 19p13 rearrangements and in identifying novel and cryptic TCF3 translocations and also acts as a tumor suppressor gene in b-cell precursor acute lymphoblastic leukemia.leukemia,
MiR-138 may be a tumor suppressor and potential prognostic biomarker in cervical cancer. Its downstream target, TCF3, may also regulate cancer development in a reverse manner as miR-138.cervical,
E2A exhibits a tumor suppressor function in human lymphoid cells.None
We conclude that inactivation of TCF3 contributes to oncogenic program of classical Hodgkin lymphomalymphoma,
SLUG, a ces-1-related zinc finger transcription factor gene with antiapoptotic activity, is a downstream target of the E2A-HLF oncoprotein. None
Regulation of annexin II by cytokine-initiated signaling pathways and E2A-HLF oncoprotein. None
TEF, an antiapoptotic bZIP transcription factor related to the oncogenic E2A-HLF chimera, inhibits cell growth by down-regulating expression of the common beta chain of cytokine receptors. None
Oligomeric self-association contributes to E2A-PBX1-mediated oncogenesis.None
The AD1 and AD2 transactivation domains of E2A are essential for the antiapoptotic activity of the chimeric oncoprotein E2A-HLF. None