| TRbeta gene could function as a tumor suppressor gene. TRbeta could serve as a novel therapeutic target in thyroid cancer. | thyroid, |
| TRs could function as tumor suppressors in a mouse model of metastatic follicular thyroid cancer. | thyroid, |
| microRNAs up-regulated in papillary thyroid carcinoma tumors directly inhibit the expression of THRB, an important tumor suppressor gene | thyroid, |
| The TR/DKK4/Wnt/beta-catenin cascade influences the proliferation and migration of hepatoma cells during the metastasis process and support a tumor suppressor role of the thyroid hormone receptor. | thyroid, |
| The present studies uncovered a novel mechanism by which thyroid hormone receptor beta could function as a tumor suppressor through modulation of TNF alpha-IkappaB alpha-NFkappaB pathway. | thyroid, |
| These data indicate that m-TRbeta1 can act as a tumor suppressor in hepatocarcinoma and its role was significantly better than that of TRbeta1. | None |
| TRbeta2-46 is an oncogenic thyroid hormone receptor isoform that promotes SKP2 expression and SKP2-dependent retinoblastoma cell proliferation. | retinoblastoma,thyroid, |