| Alterations of oncogenes, tumor suppressor genes and growth factors in hepatocellular carcinoma: with relation to tumor size and invasiveness. | liver, |
| Induction and apoptotic regression of lung adenocarcinomas by regulation of a K-Ras transgene in the presence and absence of tumor suppressor genes. | lung, |
| Modulation of signal transducer and activator of transcription 3 activities by p53 tumor suppressor in breast cancer cells. | breast, |
| Squamous cell carcinoma of the head and neck shows a high incidence of p53 tumor suppressor gene alterations; the latter therefore appears to play an important role in the pathogenesis and progression of such neoplasms. | neoplasm,HNSC, |
| Data show that activated protein C directly prevents apoptosis in hypoxic human brain endothelium through transcriptionally dependent inhibition of tumor suppressor protein p53. | brain, |
| ING1 expression is frequently associated with Adenocarcinoma of the esophagogastric junction tumorigenesis, further supporting its role as a tumor suppressor gene, and ING1 expression is independent of p53 status | gastric, |
| Lyn tyrosine kinase inhibits nuclear export of the p53 tumor suppressor in breast neoplasms | neoplasm,breast, |
| role of p53 gene in the biophysics and biology in murine erythroleukemia cell line with the goal of understanding the influence of this tumor suppressor gene on the deformability and metastasis of tumor cells | leukemia, |
| The p53 tumor suppressor pathway is disrupted in most oral squamous cell carcinomas at the cellular levels, due to either an abnormality in p53 itself or loss of expression of p53 regulatory factors. | oral |
| VHL-mediated p53 upregulation may contribute to pVHL_s tumor suppressive functions in renal cell carcinoma | kidney, |
| expression of COX-2 may be induced in serous ovarian carcinomas by loss of tumor suppressor genes such as p53 and SMAD4 and by amplification of HER-2/neuoncogene | ovarian, |
| p28 expression resulted in an accumulation of hypophosphorylated retinoblastoma protein (pRb), tumor suppressor p53, and cyclin-dependent kinase (Cdk) inhibitor p21(Cip1). | retinoblastoma, |
| p53 protein expression is closely associated with decidual transformation indicates a novel role for this tumor suppressor in regulating human endometrial function. | endometrial, |
| Aberrant expression of tumor suppressor genes and their association with chimeric oncogenes in pediatric acute lymphoblastic leukemia. | leukemia,pediatric, |
| TAp63alpha may promote thyroid tumour progression by inactivating the tumour suppressor activity of p53. | thyroid, |
| transcription factor p63 is a homologue of the tumor suppressor p53. Unlike p53, which is dispensable for normal development, p63 is critical for the development of stratified epithelial tissues such as epidermis, breast, and prostate. | breast,prostate, |
| BTG2 expression was found to be significantly reduced in a large proportion of human kidney and breast carcinomas, suggesting that BTG2 is a tumor suppressor that links p53 and Rb pathways in human tumorigenesis. | breast,kidney, |
| [Rhabdomyosarcoma development in Trp53/fos mutant mice: tumor suppressor functions of the Fos protooncogene]. | sarcoma, |
| The transformation of melanocytes to melanoma cells is characterised by abnormal proliferation due to cell cycle alterations. This occurs through alterations in the retinoblastoma (Rb) and p53 tumour suppressor pathways. | skin,retinoblastoma, |
| The Wnt signaling pathway has tumor suppressor properties in retinoblastoma. | retinoblastoma, |