| In this immunohistochemical study, 80% of all vulvar intra-epithelial neoplasia were negative for p53 tumor suppressor protein. | None |
| Influence of prothymosin alpha and its mutants on activity of the p53 tumor suppressor | None |
| TNAP-AID mice expressed alpha-fetoprotein and had deleterious mutations in the tumour suppressor gene Trp53, some of which corresponded to those found in human cancer. | None |
| CARF plays a dual role in regulating p53-mediated senescence and apoptosis, the two major tumor suppressor mechanisms. | None |
| the tumor suppressor p53 and its acetyltransferases CBP/p300 form a transcriptional complex that regulates the axonal growth-associated protein 43, a well-characterized pro-axon outgrowth and regeneration protein | None |
| Identification of human mitochondrial SSB (HmtSSB) as a novel protein-binding partner of tumour suppressor p53, in mitochondria. | None |
| The integration of PTEN and p53 into a common pathway for the induction of another tumor suppressor, Maspin, constitutes a tumor suppressor network of PTEN/p53/Mapsin that is operational under limited oxygen conditions. | None |
| SOX4, a new DNA damage sensor, is required for the activation of p53 tumor suppressor in response to DNA damage. | None |
| Internalization of a peptide fragment derived from p53 tumor suppressor protein in human SJSA-1 cancer cells is shown to occur via adsorption-mediated, energy-dependent pathways, resulting in accumulation of the material in endocytic vesicles. | None |
| Data show that upregulation of the p53 tumor suppressor during the restricted period of embryonic development significantly contributes to the Bst phenotype in Rpl24-deficient mice. | None |
| Suppression of tumor suppressor p53 functions together with nuclear calcium-regulated neuroprotective genes in a coordinate and synergistic manner to promote neuronal survival through the stabilization of mitochondria against cellular stresses. | None |
| cAMP levels may influence p53 function in malignant cells that retain wt p53, potentially affecting p53 both as a tumor suppressor during cancer initiation and maintenance, and as an effector of the apoptotic response to DNA-damaging agents | None |
| a central tumour suppressor, p53, enhances the post-transcriptional maturation of several miRNAs with growth-suppressive function, including miR-16-1, miR-143 and miR-145, in response to DNA damage | None |
| Mutations in the p53 gene impair its tumor suppressor function. Several of these tumor-derived p53 mutants can confer further aggressive oncogenic properties when overexpressed in p53-null cells. | None |
| The prolyl cis/trans isomerase cyclophilin 18 interacts with the tumor suppressor p53 and modifies its functions in cell cycle regulation and apoptosis. | None |
| Studies indicate that MAML1 functions as a coactivator for the tumor suppressor p53, MEF2C, beta-catenin and Notch signaling. | None |
| Data suggest that ARF antagonism of CtBP repression of Bik and other BH3-only genes may have a critical role in ARF-induced p53-independent apoptosis and tumor suppression. | None |
| A molecular mechanism by which hyper-excitation of the stress axis in turn activates the tumor suppressor p53. | None |
| these results point toward a correlation between GST P1 polymorphisms and lack of TP53 expression in cutaneous basal cell carcinoma(BCC) suggesting perhaps a crucial role for the GST P1 in expression of TP53 tumor suppressor in BCC. | None |
| Studies indicate that p53, arf and other tumor suppressors might be barriers to reprogramming somatic cells for the generation of induced pluripotent stem cells. | None |