Sentence and cancer type
Showing 261-280 of 386 items.
SentenceCancertype
Tumor suppressor protein (p)53, is a regulator of NF-kappaB repression by the glucocorticoid receptor.None
NIRF constitutes a nodal point in the cell cycle network and is a candidate tumor suppressor.None
Study provides a molecular mechanism involving protein deubiquitination that connects two important tumor suppressors, p53 and Beclin1.None
In HeLa cells, PNR stimulated tumor suppressor p53-responsive promoters in a tumor suppressor p53-dependent fashion and induced apoptosis in several cell types.None
OD extracts enhance the tumor suppressor p53 expression as a result of an increased binding of ERalpha/Sp1 complex to the p53 promoter region.None
Novel insights into the tumor suppressive functions of p53. [Review]None
the p53 CTD is a positive regulator of p53 tumor suppressor functionsNone
results define a mechanism of p53 inactivation during the cell cycle and imply that oncogenic hyperactivation or overexpression of Aurora B may compromise the tumor suppressor function of p53None
The adenoviral oncoprotein E1B-55K is a substrate of the SUMO conjugation system, which is directly linked to its C-terminal phosphorylation. This connection regulates the modulation of the tumor suppressor p53/chromatin-remodeling factor Daxx by E1B-55K.None
All assessments of p53 functions in vivo undermine the view that miR-34 functions as a tumor suppressor or is an essential component of the p53-tumor suppression network.None
these results demonstrate allele specificity between gain-of-function (GOF) p53 mutants and attempt to show that the specificity is dependent on the transactivation property of GOF p53; it also suggests importance of p21 activation in tumor suppression by p53.None
These results strongly suggest that CLCA2 is involved in the p53 tumor suppressor network and has a significant effect on cell migration and invasion.None
The pleiotropic nature of miRNA-10b was due to its suppression of multiple tumor suppressors, including TP53, FOXO3, CYLD, PAX6, PTCH1, HOXD10 and NOTCH1.None
mice, p66Shc contributes to tumor initiation, in particular upon activation by carcinogens as well as when p53- mediated tumor suppression mechanisms defectNone
Tumor suppressor p53 controls neural stem cell proliferation and differentiation via Id1.None
our data suggest that p63 regulates GCTSC proliferation by binding to the CDC2 and CDC25C p53-REs, which may inhibit the p53 tumor suppressor activity and contribute to GCT tumorigenesis.None
Crystal structures of the DNA-binding domain tetramer of the p53 tumor suppressor family member p73 bound to different full-site response elementsNone
Dosage-dependent tumor suppression by histone deacetylases 1 and 2 through regulation of c-Myc collaborating genes and p53 function.None
adhesion regulatory protein supervillin increases cell survival by decreasing levels of the tumor suppressor protein p53 and downstream target genesNone
results showed that both the tumor suppressor gene p53 and NF-kappaB p65 subunit suppressed the TGF-beta1-induced increase in pri-miR-224 expression in follicular granulosa cellsNone