Sentence and cancer type
Showing 121-140 of 386 items.
SentenceCancertype
Analyzing tumor suppressor activities in the murine small intestine.None
p53 has different modes of high affinity DNA binding which are related to its tumor suppressor functionsNone
Loss of Bard1, the heterodimeric partner of the Brca1 tumor suppressor, results in early embryonic lethality and chromosomal instability.None
transcription of the p53 gene is induced by IFN-alpha/beta, accompanied by an increase in p53 protein level, contributing to tumour suppression and critical for antiviral defenceNone
Transcription of the IGF-IR gene is under inhibitory control by a number of transcription factors with tumor suppressor activity, including BRCA1 and p53.None
Results describe the structural effects of the R249S mutation in the DNA-binding core domain of the tumour suppressor protein p53.None
v-Fos-stimulated invasion is independent of the pRb/p16(INK4a) and p53 tumor suppressor pathways and telomeraseNone
SIVA is a direct transcriptional target for the tumor suppressors p53 and E2F1None
DNA damage tumor suppressor genes and genomic instability.None
Pifithrin-alpha inhibits p53 signaling after interaction of the tumor suppressor protein with hsp90 and its nuclear translocationNone
Repression of the Arf tumor suppressor by E2F3 is required for normal cell cycle kinetics.None
Emerging evidence in this review discusses a key survival/death checkpoint in both peripheral and central neurons that involves the p53 tumor suppressor and its newly discovered family members, p73 and p63.None
describes that lactoferrin specifically transactivates the p53 tumor suppressor gene through the activation of nuclear factor-kappaB and consequently regulates p53-responsive oncogenesNone
Tax promotes cellular proliferation through activation of the NF-kappaB pathway while inhibiting the cell-cycle checkpoint and apoptotic function of the tumor suppressor gene p53 [review]None
maspin tumor suppressor expression is induced by p53 or TAp63gammaNone
Epigallocatechin-3-gallate increased expression of tumor suppressor protein p53 in brest cancer cells.None
Mdm2 activity could activate p53 tumor suppression REVIEWNone
p73, through HDM2, can oppose p53 tumor suppressor function and possibly contribute to tumorigenesisNone
Specific silencing of p53 abrogated the antiviral effect of SD.IFN-beta, suggesting that the tumor suppressor is critically involved in antiviral defense mediated by intracellular IFN.None
demonstrated that epigallocatechin-3-gallate activates growth arrest and apoptosis primarily via tumor suppressor p53-dependent pathway that involves the function of both p21 protein and Bax proteinNone