| TAp73 knockout shows genomic instability with infertility and tumor suppressor functions. | None |
| the transcriptionally active TAp73alpha tumor suppressor is implicated in the apoptosis induced by netrin-1 in a p53-independent and DCC/ubiquitin-proteasome dependent manner. | None |
| Data demonstrate that the long-term suppression of Plk1 increases the levels of cyclin-dependent kinase inhibitor p21(WAF1/CIP), which is partially induced by the elevated tumor suppressor p73 in p53-inactivated HeLa cells. | None |
| acetylation status of E2F-1 contributes to the selective activation of tumor suppressor p73 gene. | None |
| Deregulated expression of E2F1 promotes proteolytic degradation of tumor suppressor p73 and inhibits its transcriptional activity. | None |
| DNA methylation analysis of tumor suppressor genes in monoclonal gammopathy of undetermined significance. | None |
| tumor suppressive properties of p73 are highly dependent on cellular context, wherein p73 plays a major role in T cell development and neoplasia | None |
| The tumor suppressor protein p73 upregulated expression of Bak by utilizing different binding sites within the bak promoter. | None |
| The p73 tumor suppressor is targeted by Pirh2 RING finger E3 ubiquitin ligase for the proteasome-dependent degradation. | None |
| review of the role of p73 as a tumor suppressor and how it is regulated [review] | None |
| By a novel, reversible dynamic mechanism TNF-alpha-induced c-REL/DeltaNp63alpha interactions inactivate tumor suppressor TAp73 function, promoting TNF-alpha resistance & cell survival in cancers with mtTP53. | None |
| RanBP9 physically interacts with the tumor suppressor p73 and increases endogenous p73alpha levels at both transcriptional and post-translational levels. | None |
| Tyrosine-99 phosphorylation determines the regulation of tumor suppressor p73. | None |
| Data indicate tumor suppressors TP73, RASSF1A, MLH1 and BRCA1 as possible biomarkers to distinguish Pleomorphic invasive lobular cancer (pleomorphic ILC} from classic ILC and infiltrative ductal cancer (IDC). | None |
| In the present study, we provide evidence that the tumor suppressor gene p73 is highly susceptible to Mn-induced neurotoxicity in the nigrostriatal system. | None |
| Findings reinforce the role of TAp73 as tumor suppressor gene and indicate that the regulation of cellular metabolism by TAp73 contributes to its tumor suppressor function. | None |
| Results suggest that the loss of tumor suppressor protein p73 (p73) during the embryonic period is critical for hydrocephalus development. | None |
| The XBP1-s suppresses the expression of tumor suppressor TAp73, a member of p53 family with high homology with p53, by directly binds to TAp73 promoter and suppresses its transcriptional activity. | None |
| P73 role and expression during tumor suppression.HES1 and ECM1 are transcriptionally repressed by p73. | None |
| Inhibition of tumor suppressor p73 by nerve growth factor receptor via chaperone-mediated autophagy | None |