Sentence and cancer type
Showing 41-60 of 61 items.
SentenceCancertype
FDXR regulates TP73 tumor suppressor via IRP2 to modulate aging and tumor suppressionNone
MCL1 binds and negatively regulates the transcriptional function of tumor suppressor p73None
overexpression in malignant and premalignant lesions suggests role in oncogenic process in cervical epitheliumcervical,
Differential expression of p53 gene family members p63 and p73 in head and neck squamous tumorigenesis. HNSC,
p63 and p73 expression may represent an early event in head and neck squamous carcinoma tumorigenesis and may function as oncogenes in the development of these tumors.HNSC,
p73 has a role in contributing to the oncogenic potential of neuroblastoma cells (review)neuroblastoma,
[Expression and prognosis significance of p73 and PCNA in laryngeal squamous cell carcinoma]. laryngeal,
p73 protein positive expression may play a part in laryngeal squamous cell carcinoma progression and function as an oncogene in the development of LSCC.laryngeal,
The p73-isoform-related interaction with Sp1 is the underlying mechanism of the diverse outcome on HBV core expression, suggesting a new mechanism by which oncogenic DeltaTAp73 could enhance the carcinogenic process in liver cells.liver,
The molecular mechanisms accounting for the oncogenic role of DeltaNp73 in hepatocellular carcinoma, were investigated.liver,
DeltaNp73 behaves as an oncogene that targets p53 that might explain why DeltaNp73 upregulation may be selected for during tumorigenesisNone
reported overexpression of p73alpha in certain tumor types, and this study_s findings that p73alpha exerts anti-apoptotic functions, indicate a potential oncogenic activity for p73None
The overall data argue against an oncogenic role for isoform DeltaNp73.None
findings show that deltaN-p73 is a transcriptional target of the PML/RARalpha oncogene; this results in the transcriptional repression of deltaN-p73None
Antisense gapmers selectively suppress individual oncogenic p73 splice isoforms and inhibit tumor growth in vivo. None
upregulation of DeltaTAp73 isoforms was associated with shortened OS, increase in proliferation, and drug resistance confirms their oncogenic role and plausible value as prognostic markers.None
Knockdown of p73 inhibits proto-oncogene, pleomorphic adenoma gene-like 2-induced cell cycle block and Bax expression.None
reported that DeltaNp73 exhibits anti-apoptotic and oncogenic properties through inhibition of p53 and p73 proteinsNone
The p73 gene may play a role as oncogene in Wilms_ tumor patients with p73 gene promoter methylation and mRNA overexpression is associated with promoter methylation status of p73 gene.None
[Relationship between mRNA expression and promoter methylation status of p73 gene in peripheral blood among children with Wilms tumor]. None