Showing 1-3 of 3 items.

Sentence	Cancertype
Expression of a Y-located human proto-oncogene TSPY in a transgenic mouse model of prostate cancer.	prostate,
Experimental evidence establishes TSPY1 as an oncogenic factor that facilitates tumor progression and causes poor prognosis in male patients with lung adenocarcinoma or hepatocellular carcinoma. These findings revealed that TSPY1 strongly promotes the activation of the PI3K/AKT and RAS signaling pathways through suppressing IGFBP3 gene transcription.	liver,lung,
TSPY could exert its oncogenic function(s) by interacting with eEF1As and stimulating gene expression via its enhancements in protein synthesis and gene transcription	None