| A Paradoxical Tumor-Suppressor Role for the Rac1 Exchange Factor Vav1 in T Cell Acute Lymphoblastic Leukemia | leukemia, |
| An unexpected tumor suppressor role for VAV1(a) | None |
| DNA methylation and oncogene expression in methapyrilene-induced rat liver tumors and in treated hepatocytes in culture. | liver, |
| The results highlight for the first time the potential role of Vav1 as an oncogenic stress activator in cancer and the p53 dependence of its pro-apoptotic effect in breast cells. | breast, |
| Tyrosine phosphorylation of the proto-oncogene product Vav and its association with the adapter Grb2/Ash in a human leukemia cell line UT-7. | leukemia, |
| The oncogene product Vav is a crucial regulator of primary cytotoxic T cell responses but has no apparent role in CD28-mediated co-stimulation. | None |
| Caspase-dependent cleavage and inactivation of the Vav1 proto-oncogene product during apoptosis prevents IL-2 transcription. | None |
| Genomic organization and regulation of the vav proto-oncogene. | None |
| Lack of interferon-alpha-induced tyrosine phosphorylation of Vav proto-oncogene in patients with myelofibrosis with myeloid metaplasia. | None |
| Association of Bcr-Abl with the proto-oncogene Vav is implicated in activation of the Rac-1 pathway | None |
| Association of Bcr-Abl with the proto-oncogene Vav is implicated in activation of the Rac-1 pathway. | None |
| PU.1 regulates the expression of the vav proto-oncogene. | None |
| Tyrosine phosphorylation of the vav proto-oncogene product in activated B cells. | None |
| Tyrosine phosphorylation of vav proto-oncogene product containing SH2 domain and transcription factor motifs. | None |
| The hematopoietically expressed vav proto-oncogene shares homology with the dbl GDP-GTP exchange factor, the bcr gene and a yeast gene (CDC24) involved in cytoskeletal organization. | None |
| Phylogenetic conservation of the regulatory and functional properties of the Vav oncoprotein family. | None |
| Oncogenic Vav1 induces Rac-dependent apoptosis via inhibition of Bcl-2 family proteins and collaborates with p53 deficiency to promote hematopoietic progenitor cell proliferation. | None |
| oncogenic Vav1 enhances both proliferation and self-renewal of hematopoietic progenitor cells | None |
| Overexpression of the VAV proto-oncogene product is associated with B-cell chronic lymphocytic leukaemia displaying loss on 13q. | None |
| Osteopontin is an oncogenic Vav1- but not wild-type Vav1-responsive gene: implications for fibroblast transformation. | None |