Sentence and cancer type
Showing 101-120 of 137 items.
SentenceCancertype
Novel insights into the role of the tumor suppressor von Hippel Lindau in cellular differentiation, ciliary biology, and cyst repression.None
Hypoxia inactivates the VHL tumor suppressor through PIASy-mediated SUMO modification.None
Drosophila von Hippel-Lindau tumor suppressor gene function in epithelial tubule morphogenesis.None
The predicted 14 amino acid extended mutant von Hippel-Lindau tumor suppressor protein variant was stable and retained the ability to downregulate hypoxia-inducible factor 1 alpha in a hydroxylation dependent mannerNone
The autosomal dominantly inherited disorder von Hippel-Lindau disease (VHL) is caused by germline mutations in the VHL tumour suppressor gene (TSG). (Review)None
Myb-binding protein p160 is a novel target of the von Hippel-Lindau tumor suppressor.None
Cancer cells promote survival through depletion of the von Hippel-Lindau tumor suppressor by protein crosslinking.None
results suggest a novel mechanism of regulation of the VHL tumor suppressor by TGase 2 that appears to be independent of the known cancer regulatory mechanismsNone
Von Hippel-Lindau gene product directs cytokinesis: a new tumor suppressor function.None
Kelch-like 20 up-regulates the expression of hypoxia-inducible factor-2?? through hypoxia- and von Hippel-Lindau tumor suppressor protein-independent regulatory mechanisms.None
The von Hippel-Lindau tumor suppressor protein promotes c-Cbl-independent poly-ubiquitylation and degradation of the activated EGFR.None
The interaction of the von Hippel-Lindau tumor suppressor and heterochromatin protein 1.None
PIAS4 interacts with the tumour suppressor von Hippel-Lindau (VHL) and leads to VHL sumoylation, oligomerization, and impaired function.None
A novel function of pVHL and demonstrate a negative-feedback loop between pVHL and E2F1, which may shed new light on the explanation of the role of pVHL in tumour suppression.None
Interaction between Nm23 and the tumor suppressor VHLNone
Data show the spectrum of von Hippel-Lindau disease tumor suppressor (VHL) protein mutations in Korean von Hippel-Lindau (VHL) disease.None
RSUME is expressed in VHL tumors and inhibits VHL and regulates its tumor suppressor function.None
Age-specific risk for CNS hemangioblastoma was significantly higher in subjects carrying missense mutations in alpha domain in exon 1; beta domain in exon 3 of von Hippel-Lindau tumor suppressor within the HIF-alpha binding site.None
Hydroxylation-Dependent Interaction of Substrates to the Von Hippel-Lindau Tumor Suppressor Protein (VHL)None
Data show the interactions between von Hippel-Lindau tumor suppressor (VHL) and the cyclin-dependent kinase inhibitor family CDKN1 (p21, p27 and p57).None