Sentence and cancer type
Showing 101-120 of 120 items.
SentenceCancertype
The role of WT1 in oncogenesis: tumor suppressor or oncogene?. None
Identification of a DNA-binding site and transcriptional target for the EWS-WT1(+KTS) oncoprotein. None
Improved human T-cell responses against synthetic HLA-0201 analog peptides derived from the WT1 oncoprotein. None
A tumor suppressor and oncogene: the WT1 story. None
WT1 expression is induced by oncogenic signalling from BCR/ABL1. WT1 contributes to resistance against apoptosis induced by imatinib.None
HtrA2, taming the oncogenic activities of WT1. None
Wilms tumours: about tumour suppressor genes, an oncogene and a chameleon gene. None
Targeting the intracellular WT1 oncogene product with a therapeutic human antibody. None
Both isoforms of the EWS/WT1 fusion protein can function as an oncogene in desmoplastic small round cell tumors.None
The oncogenic properties of EWS/WT1 of desmoplastic small round cell tumors are unmasked by loss of p53 in murine embryonic fibroblasts. None
Therapeutic efficacy of an Fc-enhanced TCR-like antibody to the intracellular WT1 oncoprotein. None
In this review, WT1 is a master regulator of organ development, a tumor suppressor and an oncogene.None
WT1-mediated repression of the proapoptotic transcription factor ZNF224 is triggered by the BCR-ABL oncogene. None
Therapeutic bispecific T-cell engager antibody targeting the intracellular oncoprotein WT1. None
Multiple studies provide evidence that WT1 plays a significant role in a variety of cancers occurring mainly in childhood and adolescence, but with involvement in some adult cancers. Also, Wt1 has a tumor suppressive function and oncogenic properties as well.None
we report that CUG initiation site for WT1 protein synthesis (CUG)-translated WT1 (cugWT1), an N-terminally extended form of canonical AUG initiation site for WT1 protein synthesis (AUG)-translated WT1 (augWT1), was overexpressed in most cancer cell lines and cancer tissues and functioned as an oncogeneNone
Chromosome translocation-mediated conversion of a tumor suppressor gene into a dominant oncogene: fusion of EWS1 to WT1 in desmoplastic small round cell tumors. None
The DNA binding domains of the WT1 tumor suppressor gene product and chimeric EWS/WT1 oncoprotein are functionally distinct. None
The Wilms tumor 1 gene: oncogene or tumor suppressor gene?. None
The desmoplastic small round cell tumor t(11;22) translocation produces EWS/WT1 isoforms with differing oncogenic properties. None