Sentence and cancer type

Showing 1-10 of 10 items.

Sentence	Cancertype
LncRNA XIST acts as a tumor suppressor in prostate cancer through sponging miR-23a to modulate RKIP expression	prostate,
XIST positively regulated the expression of P21 through sponging miR-106b-5p, and played a tumor suppressor role in renal cell carcinoma.	kidney,
Data suggest a tumor suppressor role of Xist in inhibiting AKT activation via regulation of non-X-chromosome gene PHLPP1 expression.	None
Data suggest that XIST is upregulated in a variety of non-sex-related human cancers, whereas it is lost in some female cancers. XIST acts as a tumor suppressor or an oncogene in different tumors. The contradictory functions of XIST in different cancers may be largely attributed to differences in tumor tissue origin, extracellular microenvironment, and upstream and downstream regulatory factors. [review]	None
Xist noncoding RNA could act as a tumor suppressor gene in patients with classical Hodgkin_s disease.	None
XIST functioned as an oncogene in nasopharyngeal carcinoma through up-regulating E2F3 in part through _spongeing_ miR-34a-5p.	nasopharyngeal,laryngeal,
Long noncoding RNA XIST acts as an oncogene in non-small cell lung cancer by epigenetically repressing KLF2 expression.	lung,
MiR-186-5p overexpression blocked the oncogenic effects of XIST on cell proliferation and invasion, suggesting that the effects of XIST on non-small cell lung cancer growth and invasion are partially mediated by miR-186-5p.	lung,
These findings indicated that XIST may regulate the tumor growth and metastasis via miR-140-dependent iASPP regulation. Taken together, our data indicated that XIST may be an oncogenic lncRNA that promotes the proliferation and metastasis of lung cancer through the regulation of miR-140 and could be regarded as a therapeutic target in human lung cancer.	lung,
lncRNA XIST is a potential oncogene in colorectal cancer (CRC), and could promote CRC cell proliferation through inhibiting miR-132-3p.	colorectal,