| These results revealed ZIC1 as a novel candidate tumor suppressor gene downregulated through promoter hypermethylation in gastric cancer. | gastric, |
| ZIC1 is downregulated through promoter hypermethylation, and functions as a tumor suppressor gene in colorectal cancer. | colorectal, |
| Methylation of ZIC1, a putative tumor suppressor, may be a novel determinant of ovarian cancer outcome | ovarian, |
| ZIC1 is frequently inactivated by promoter hypermethyaltion and functions as a tumor suppressor in thyroid cancer through modulating PI3K/Akt and MAPK signaling pathways and transcription factor FOXO3a. | thyroid, |
| Study demonstrate that ZIC1 plays a tumor suppressive role in breast cancer, by targeting surviving, significantly downregulating its expression. | breast, |
| ZIC1 may potentially function as a tumor suppressor gene | None |