| miR-454 functions as a tumor suppressor in glioblastoma, inhibiting proliferation of human glioblastoma cells by suppressing PDK1 expression. | glioblastoma, |
| miR-454-3p Is an Exosomal Biomarker and Functions as a Tumor Suppressor in Glioma | glioma, |
| Data found that miR-454-3p expression was significantly decreased in both glioblastoma (GBM) tissues and cultured cell lines. Its overexpression suppressed cell proliferation and induced apoptosis of GBM. miR-454-3p executed the tumor suppressive activity via downregulating NFATc2 in GBM. | GBM,glioblastoma, |
| The oncogenic role of microRNA-130a/301a/454 in human colorectal cancer via targeting Smad4 expression. | colorectal, |
| miR-454 functions as an oncogene by inhibiting CHD5 in hepatocellular carcinoma. | liver, |
| MicroRNA-454 functions as an oncogene by regulating PTEN in uveal melanoma. | skin, |