| BTG2 expression was found to be significantly reduced in a large proportion of human kidney and breast carcinomas, suggesting that BTG2 is a tumor suppressor that links p53 and Rb pathways in human tumorigenesis. | breast,kidney, |
| PC3 / BTG2 acts as a tumor suppressor of medulloblastoma by its antiproliferative and prodifferentiative effect on cerebellar progenitors. This antagonizes Shh and appears physiologic since endogenous PC3 / BTG2 decreases in human medulloblastomas. | medulloblastomas, |
| we show that the putative tumor suppressor gene Btg2 is consistently downregulated in high grade gliomas and that its downregulation is necessary for a cell to maintain the malignant phenotype. | glioma, |
| The human BTG2/TIS21/PC3 gene: genomic structure, transcriptional regulation and evaluation as a candidate tumor suppressor gene. | None |
| PC3/Tis21/BTG2 is a tumor suppressor of medulloblastoma | None |
| Estradiol downregulation of the tumor suppressor gene BTG2 requires estrogen receptor-alpha and the REA corepressor | None |
| Skp2 enhances polyubiquitination and degradation of TIS21/BTG2/PC3, tumor suppressor protein, at the downstream of FoxM1. | None |
| Tumor suppressors BTG1 and BTG2 regulate early mouse B-cell development. | None |