| role of the BHLHB3 protein as a tumor suppressor for lung cancer. | lung, |
| the present study indicated that SHARP1 acts as a tumor suppressor in thyroid cancer and that its downregulation may contribute to the proliferation, migration and invasion of thyroid cancer cells through mechanisms possibly involving HIF1alpha | thyroid, |
| DEC2 Serves as Potential Tumor Suppressor in Breast Carcinoma | breast, |
| The expression of BHLHE41 in clear cell renal cell carcinoma (ccRCC) was significantly increased in microarray datasets, RNA sequencing data, and in fresh ccRCC tissue samples, compared with than their adjacent nontumorous controls. BHLHE41 knockdown reduced cell proliferation and migration of A498 and CAKI1 cells. These observations demonstrated that BHLHE41 could be a biomarker and an oncogene for ccRCC. | kidney, |