| in addition to its role in brain development, MCPH1 also functions as a tumor suppressor gene and is regulated by miR-27a | brain, |
| BRIT1 regulates p53 stability and functions as a tumor suppressor in breast cancer. | breast, |
| in addition to its role in brain development, MCPH1 also functions as a tumor suppressor gene and is directly regulated by miR-27a. | brain, |
| Candidate tumor suppressor gene MCPH1 is mutated in colorectal and gastric cancers. | gastric,colorectal, |
| BRIT1 is a crucial DNA damage regulator in the ATM/ATR pathways and suggest that it functions as a tumor suppressor gene | None |
| MDC1 and BRIT1 may function as tumor-suppressor genes, at least in part by orchestrating proper centrosome duplication and mitotic spindle assembly. | None |
| Mcph1 controls centrosome numbers after DNA damage, which may indicate a novel tumour suppressive mechanism for microcephalin. | None |
| MCPH1 is a bona fide tumor suppressor gene. | None |
| Tumor suppressor functions of MCPH1/BRIT1 and BRCA1; links with the inactivation of the functional form of hTERT and the activation of dominant negative splice variants of hTERT. | None |
| Tumor suppressor MCPH1 regulates gene expression profiles related to malignant conversion and chromosomal assembly | None |