| A new somatic frameshift mutation of a tumor suppressor gene PALB2 has been identified in patients with gastric and colorectal cancers with microsatellite instability. | gastric,colorectal, |
| Individual deletion of Palb2, Brca1 or Brca2 genes in pancreas per se using Pdx1-Cre was insufficient to cause tumors, but it reduced pancreata size. Concurrent expression of mutant KrasG12D and p53R270H, with tumor suppressor inactivated strains in Palb2-KPC, Brca1-KPC or Brca2-KPC, accelerated pancreatic ductal adenocarcinoma (PDAC) development. | pancreatic, |
| Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2. | None |
| BRCA2 fusion peptide deleted for the DNA binding domain and active in homologous recombination is completely dependent on interaction with the PALB2 tumor suppressor for activity | None |
| overview of the molecular mechanisms that underlie the tumour suppressor function of PALB2; also provide a molecular description of Fanconi_s anaemia- or cancer-associated PALB2 mutations [review] | None |
| Cancer-causing mutations in the tumor suppressor PALB2 reveal a novel cancer mechanism using a hidden nuclear export signal in the WD40 repeat motif | None |
| The tumor suppression mechanisms of the BRCA1-PALB2 DNA damage response pathway. | None |
| The Tumor Suppressor PALB2: Inside Out | None |
| A global functional analysis of missense mutations reveals two major hotspots in the PALB2 tumor suppressor | None |