| NOR-1 is a critical tumor suppressor of myeloid leukemogenesis that is downregulated in leukemic blasts from acute myeloid leukemia patients. | leukemia, |
| The authors discuss the role of NR4A1 and NR4A3 as tumor suppressors in hematologic neoplasms.[Review] | neoplasm, |
| aberrant JAK/STAT3 signaling epigenetically silences a potential tumor suppressor, NR4A3, in gastric cancer, plausibly representing a reliable biomarker for gastric cancer prognosis | gastric, |
| Possible role of intragenic DNA hypermethylation in gene silencing of the tumor suppressor gene NR4A3 in acute myeloid leukemia | leukemia, |
| Transcript analysis of four different aggressive lymphoma cell lines overexpressing either NR4A3 or NR4A1 revealed that apoptosis was driven similarly by induction of BAK, Puma, BIK, BIM, BID, and Trail. Overall, our results showed that NR4A3 possesses robust tumor suppressor functions of similar impact to NR4A1 in aggressive lymphomas | lymphoma, |
| The tumor suppressor NOR1 suppresses cell growth, invasiveness, and tumorigenicity in glioma | glioma, |
| It has been concluded that NR4A3 is upregulated through enhancer hijacking and has important oncogenic functions in acinic cell carcinomas of the salivary glands. | None |