Sentence and cancer type
Showing 1-18 of 18 items.
SentenceCancertype
genes mutated in ovarian clear cell carcinoma(OCCC);data suggest PPP2R1A functions as an oncogene and ARID1A as tumor-suppressor gene; in 42 OCCCs, 7% had mutations in PPP2R1A and 57% in ARID1A; suggests aberrant chromatin remodeling contributes to OCCCovarian,
These data implicate ARID1A as a tumor-suppressor gene frequently disrupted in ovarian clear-cell and endometrioid carcinomas.ovarian,
Inactivating mutations of the ARID1A tumor suppressor gene are the most common in endometriosis related ovarian neoplasms.neoplasm,ovarian,
ARID1A may serve as an important tumor suppressor in NSCLC.lung,
Our results indicate that the Arid1a tumour suppressor gene has a key role in regulating ovarian endometrioid carcinoma differentiationovarian,
Loss of Tumor Suppressor ARID1A Protein Expression Correlates with Poor Prognosis in Patients with Primary Breast Cancerbreast,
Arid1a Has Context-Dependent Oncogenic and Tumor Suppressor Functions in Liver Cancerliver,
ARID1A may serve as a tumour suppressor in osteosarcoma progression.osteosarcoma,
Arid1a Has Context-Dependent Oncogenic and Tumor Suppressor Functions in Liver Cancerliver,
Our data provide additional evidence that AT-rich interactive domain 1A might function as a tumor suppressor gene in pancreatic carcinogenesis.pancreatic,
Genomic and functional evidence for an ARID1A tumor suppressor role.None
ARID1A is a bona fide tumor suppressor that collaborates with p53 to regulate CDKN1A and SMAD3 transcription and tumor growth in gynecologic cancers.None
gene mutation of ARID1A led to absence of the encoded protein and inactivation of the tumor suppressor.We found that FIGO stage I and II patients with negative tumor expression of ARID1A might have a worse prognosis.None
Prognostic role and implications of mutation status of tumor suppressor gene ARID1A in cancer: a systematic review and meta-analysisNone
Inactivating ARID1A Tumor Suppressor Enhances TERT Transcription and Maintains Telomere Length in Cancer CellsNone
ARID1A has a complex role in tumor suppression. Mutations in ARID1A occur in a broad spectrum of tumor types, yet show high selectivity within tumors from the same tissue of originNone
The Tumor Suppressor ARID1A Controls Global Transcription via Pausing of RNA Polymerase IINone
Remodeling of the ARID1A tumor suppressorNone