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Cancertype
Sesn2 is a potential tumor suppressor in lung epithelial cells. The expression level of Sesn2 may serve as a prognostic marker for Chinese lung cancer patients in the clinic.
lung,
These results highlight Sestrin2 as a novel tumor suppressor, whose downregulation can accelerate both colitis and colon carcinogenesis.
colorectal,
Sesn2 is oncogenic in skin squamous cell carcinoma and melanoma.
skin,