Showing 41-44 of 44 items.

Sentence	Cancertype
RUNX3 is a novel negative regulator of oncogenic TEAD-YAP complex in gastric cancer.	gastric,
RUNX3 in oncogenic and anti-oncogenic signaling in gastrointestinal cancers.	None
Our results from clinical samples also suggest that Threonine 209 phosphorylation by Pak1 could be a potential therapeutic target and of great clinical relevance with implications for Runx3 inactivation in cancer cells where Runx3 is known to be oncogenic. The findings presented in this study provide evidence of Runx3-Threonine 209 phosphorylation as a molecular switch in dictating the tissue-specific dualistic functions	None
Post-translational modifications of RUNX3 have been shown to play an important role in directing RUNX3 functions. In cancer, RUNX3 functions as tumor suppressor or oncogene depending on its phosphorylation status by PAK1. [review]	None