| Taken together, our data suggest that Numb may possibly function as a tumor suppressor involved in the carcinogenesis of clear cell renal cell carcinoma | kidney, |
| Numb functions as a tumor suppressor in colorectal cancer, and its tumor suppressor function is mediated by negative regulation of the epithelial mesenchymal transition through the Wnt signaling pathway. | colorectal, |
| Data show that the tumor suppressors Brat and Numb regulate transit-amplifying neuroblast lineages in Drosophila. | None |
| this study identified a novel molecular determinant of breast cancer progression, uncovering a potential oncogenic role for the NUMB6 protein in cancer cell migration and invasion, coupled to the maintenance of mesenchymal-like cells. | breast, |