Showing 1-4 of 4 items.

Sentence	Cancertype
IRS2 is a candidate driver oncogene on 13q34 in colorectal cancer.	colorectal,
These data identify IRS2 as a likely driver oncogene in the prevalent 13q34 region of gain/amplification and suggest that IRS2 over-expression may provide an additional mechanism of PI3 kinase pathway activation in colorectal cancer.	colorectal,
This review discusses the roles of IRS-1 and IRS-2 in oncogenic transformation and cancer progression.	None
oncogenic transformation by v-src in mouse embryonic fibroblasts requires the association of v-src with IRS-2; IRS-2 binds src through two tyrosine residues that also bind PI3-K	None