Sentence and cancer type
Showing 1-20 of 84 items.
SentenceCancertype
CBL is highly expressed in breast cancer cells and significantly inhibits transforming growth factor-beta (TGF-beta) tumor suppressive activity.breast,
gain-of-function mutations of c-cbl tumour suppressor associated with acquired uniparental disomy in the pathogenesis of some myeloid cancersNone
C-CBL is likely to play a tumor suppressive role by antagonizing a robust oncogenic signaling driven by c-Src.None
Suppression of apoptosis and granulocyte colony-stimulating factor-induced differentiation by an oncogenic form of Cbl. colorectal,
c-Cbl associates directly with the C-terminal tail of the receptor for the macrophage colony-stimulating factor, c-Fms, and down-modulates this receptor but not the viral oncogene v-Fms. colorectal,
Identification of CBL, a proto-oncogene at 11q23.3, as a novel MLL fusion partner in a patient with de novo acute myeloid leukemia. leukemia,
A rearrangement of the c-cbl proto-oncogene in HUT78 T-lymphoma cells results in a truncated protein. lymphoma,
Is the c-Cbl proto-oncogene involved in chronic lymphocytic leukemia?. leukemia,
Evidence that sprouty 2 is necessary for sarcoma formation by H-Ras oncogene-transformed human fibroblasts. sarcoma,
Cbl and human myeloid neoplasms: the Cbl oncogene comes of age. neoplasm,
Novel oncogenic mutations of CBL in human acute myeloid leukemia that activate growth and survival pathways depend on increased metabolism. leukemia,
Casitas B lymphoma mutations in childhood acute lymphoblastic leukemia. lymphoma,leukemia,
Somatic mutations were identified in cbl oncogene protein in children with childhood acute lymphoblastic leukemia that involved deletions affecting the intron/exon boundaries of exon 8 and abolishing E3 ligase function.leukemia,
Data suggest that EPHA2 (ephrin type-A receptor 2) regulates polyubiquitination via proto-oncogene protein c-CBL, phosphorylation of clathrin, integrin signal transduction, and endocytosis of Kaposi sarcoma-associated herpesvirus into fibroblasts.sarcoma,
Oncogenic Signaling by Leukemia-Associated Mutant Cbl Proteins. leukemia,
Up-regulation of c-Cbl suggests its potential role as oncogene in primary colorectal cancer.colorectal,
v-cbl, an oncogene from a dual-recombinant murine retrovirus that induces early B-lineage lymphomas. lymphoma,
The protein product of the proto-oncogene c-cbl forms a complex with phosphatidylinositol 3-kinase p85 and CD19 in anti-IgM-stimulated human B-lymphoma cells. lymphoma,
The proto-oncogene p120(Cbl) is a downstream substrate of the Hck protein-tyrosine kinase. None
The proto-oncogene c-Cbl is a negative regulator of DNA synthesis initiated by both receptor and cytoplasmic tyrosine kinases. None