| ErbB2 and ErbB4 Cbl binding sites can functionally replace the ErbB1 Cbl binding site. | None |
| The human CBL oncogene. | None |
| AUthors discuss insights gained from the analyses of Cbl mutants both in human patients and in animal models and propose potential mechanisms of oncogenesis through this pathway. | None |
| Mutant Cbl proteins as oncogenic drivers in myeloproliferative disorders. | None |
| Study indicates that FLT3-CBL interaction sites and the AKT pathway as critical mediators of transformation by oncogenic CBL mutants. | None |
| EphrinA2 regulates clathrin mediated KSHV endocytosis in fibroblast cells by coordinating integrin-associated signaling and c-Cbl directed polyubiquitination. | None |
| The c-cbl proto-oncogene is preferentially expressed in thymus and testis tissue and encodes a nuclear protein. | None |
| c-Cbl_s linker helix region mutations are only oncogenic when they disrupt the native state and fail to ubiquitinate protein tyrosine kinases. | None |
| Identification of two murine loci homologous to the v-cbl oncogene. | None |
| Depletion of cbl proto-oncogene E3 ubiquitin-protein ligase (c-Cbl) leads to increased levels of differential display and activated by p53 protein (DDA3), resulting in increased recruitment of HK2 kinesin protein (Kif2a) to the mitotic spindle, a concomitant reduction in spindle formation, and chromosome alignment defects. c-Cbl depletion induces centrosome over-duplication and centriole amplification. | None |
| The protein product of the c-cbl oncogene rapidly complexes with the EGF receptor and is tyrosine phosphorylated following EGF stimulation. | None |
| TPO/c-mpl ligand induces tyrosine phosphorylation of multiple cellular proteins including proto-oncogene products, Vav and c-Cbl, and Ras signaling molecules. | None |
| Physical association between Src homology 3 elements and the protein product of the c-cbl proto-oncogene. | None |
| The proto-oncogene product c-Cbl becomes tyrosine phosphorylated by stimulation with GM-CSF or Epo and constitutively binds to the SH3 domain of Grb2/Ash in human hematopoietic cells. | None |
| Coupling of the proto-oncogene product c-Cbl to the epidermal growth factor receptor. | None |
| Association of a chromosome deletion syndrome with a fragile site within the proto-oncogene CBL2. | None |
| Specific association of the beta isoform of the p85 subunit of phosphatidylinositol-3 kinase with the proto-oncogene c-cbl. | None |
| Similarity of sli-1, a regulator of vulval development in C. elegans, to the mammalian proto-oncogene c-cbl. | None |
| Tyrosine phosphorylation of the c-cbl proto-oncogene protein product and association with epidermal growth factor (EGF) receptor upon EGF stimulation. | None |
| Genetic expression of the C-CBL proto-oncogene in human thymocytes. | None |