Sentence and cancer type
Showing 61-80 of 84 items.
SentenceCancertype
Tumour induction by activated abl involves tyrosine phosphorylation of the product of the cbl oncogene. None
Expression of c-cbl proto-oncogene is modulated during differentiation but not during induction of proliferation. None
The truncation that generated the v-cbl oncogene reveals an ability for nuclear transport, DNA binding and acute transformation. None
The product of the cbl oncogene forms stable complexes in vivo with endogenous Crk in a tyrosine phosphorylation-dependent manner. None
Tyrosine phosphorylation of the c-cbl proto-oncogene product mediated by cell surface antigen CD38 in HL-60 cells. None
The proto-oncogene product p120CBL and the adaptor proteins CRKL and c-CRK link c-ABL, p190BCR/ABL and p210BCR/ABL to the phosphatidylinositol-3 kinase pathway. None
Proto-oncogene products Vav and c-Cbl are involved in the signal transduction through Grb2/Ash in hematopoietic cells. None
CD38-mediated growth suppression of B-cell progenitors requires activation of phosphatidylinositol 3-kinase and involves its association with the protein product of the c-cbl proto-oncogene. None
The cbl oncogene: a novel substrate of protein tyrosine kinases. None
Interaction of the c-cbl proto-oncogene product with the Tyk-2 protein tyrosine kinase. None
Association of phosphatidylinositol 3-kinase with the proto-oncogene product Cbl upon CD38 ligation by a specific monoclonal antibody in THP-1 cells. None
The proto-oncogene product p120(cbl) links c-Src and phosphatidylinositol 3 -kinase to the integrin signaling pathway. None
Yeast two-hybrid in vivo association of the Src kinase Lyn with the proto-oncogene product Cbl but not with the p85 subunit of PI 3-kinase. None
D-Cbl, the Drosophila homologue of the c-Cbl proto-oncogene, interacts with the Drosophila EGF receptor in vivo, despite lacking C-terminal adaptor binding sites. None
Proto-oncoprotein Vav interacts with c-Cbl in activated thymocytes and peripheral T cells. None
Insulin stimulates tyrosine phosphorylation of the proto-oncogene product of c-Cbl in 3T3-L1 adipocytes. None
Efficient cellular transformation by the Met oncoprotein requires a functional Grb2 binding site and correlates with phosphorylation of the Grb2-associated proteins, Cbl and Gab1. None
Tyrosine kinase activity of the EGF receptor is enhanced by the expression of oncogenic 70Z-Cbl. None
The Cbl protooncogene product: from an enigmatic oncogene to center stage of signal transduction. None
Thymocyte activation induces the association of the proto-oncoprotein c-cbl and ras GTPase-activating protein with CD5. None