| C/EBPalpha with its associated direct core clock gene target, PER2, are highly deregulated in DLBCL, suggesting an important tumor suppressive pathway in the pathogenesis of this lymphoma entity | lymphoma, |
| Per2 acted here as a liver tumor suppressor from initiation to progression. | liver, |
| In human oral squamous cell carcinoma cells PER2 through the regulation of the numerous important downstream tumor-related genes, plays a major role in tumor suppression. | oral |
| Histone deacetylase inhibitors induce the expression of tumor suppressor genes Per1 and Per2 in human gastric cancer cells | gastric, |
| Per2 plays a role in tumor suppression and DNA damage response in mice | None |
| The circadian gene Period2 plays an important role in tumor suppression and DNA damage response in vivo. | None |
| The circadian gene mPeriod2 may play an important role in tumor suppression by inducing apoptotic cell death. | None |
| findings clearly demonstrate the tumor suppression function of PER2 and elucidate a pathway by which hypoxia promotes EMT via degradation of PER2 | None |