Sentence and cancer type
Showing 1-9 of 9 items.
SentenceCancertype
Phosphorylation of deleted in liver cancer 1 (DLC1) and DLC2 by Akt at the conserved residue points to a common regulatory mechanism of the DLC tumor suppressor family.liver,
DLC2 operates as a tumor suppressor gene in breast cancer via the RhoGTPase pathwaybreast,
Differential regulation of rho GTPases during lung adenocarcinoma migration and invasion reveals a novel role of the tumor suppressor StarD13 in invadopodia regulationlung,
Results suggest that DLC2 exhibits its tumor suppressor functions in vivo as a GAP specific for RhoA, exerting its effects in suppression of cytoskeleton reorganization, cell growth, cell migration, and transformation.None
Expression profile of the tumor suppressor genes DLC-1 and DLC-2 in solid tumors.None
The present study further describes the role of StarD13 as a tumor suppressor as well as a Rho GAP.None
Study describes STARD13 as a tumor suppressor playing a positive role in cancer motility.None
The tumor suppressor DLC2 and Kif1B are central components of a signaling network that guides spindle positioning, cell-cell adhesion and mitotic fidelity.None
Results indicate that Stard13 acts as a metastasis suppressor rather than a tumor suppressor gene, in Neu oncogene induced mammary tumorigenesis.None