Showing 1-3 of 3 items.

Sentence	Cancertype
ik3-1/Cables has been identified to be a candidate tumor suppressor for colon and head/neck cancers.	colorectal,HNSC,
Loss of Cables1 enhances tumor progression in the Apc(Min/+) mouse model and activates the Wnt/beta-catenin signaling pathway. Cables1 is a tumor suppressor gene on chromosome 18q in this in vivo mouse model.	None
Results illuminated a dynamic regulatory system through which activated Akt and 14-3-3 work directly together to neutralize a potent tumor suppressor function of Cables1.	None