| Human pituitary tumor transforming gene (hPTTG) inhibits human lung cancer A549 cell growth through activation of p21(WAF1/CIP1 ). | pituitary,lung, |
| PTTG1, an oncogene, is regulated by the liganded thyroid hormone receptor beta | thyroid, |
| Epigenetic changes of pituitary tumor-derived transforming gene 1 in pancreatic cancer. | pancreatic,pituitary, |
| The oncogene PTTG1 was overexpressed in pancreatic tumor tissues and verified by RT-PCR detection. The methylation status of DNA in promoter areas was involved in the gene expression with the help of other factors in pancreatic cancer. | pancreatic, |
| Pituitary tumor transforming gene 1 (PTTG1), an oncogene, was the most up-regulated transcript in KLF6+/- liver. PTTG1 downregulation represents a novel tumor suppressor pathway of KLF6. | liver,pituitary, |
| [review] The pituitary tumor transforming gene (PTTG) is a multifunctional proto-oncogene that is over-expressed in various tumors including thyroid carcinomas, where it is a prognostic indicator of tumor recurrence. | pituitary,thyroid, |
| The pituitary tumor transforming gene in thyroid cancer. | pituitary,thyroid, |
| Human pituitary tumor-transforming gene 1 overexpression reinforces oncogene-induced senescence through CXCR2/p21 signaling in breast cancer cells. | breast,pituitary, |
| Expression of the PTTG1 oncogene is associated with aggressive clear cell renal cell carcinoma. | kidney, |
| Expression of the PTTG1 oncogene is associated with aggressive clear cell renal cell carcinoma. | kidney, |
| PTTG1 is an independent prognostic factor and acts as an oncogene in colorectal cancer | colorectal, |
| Cell cycle regulated expression and phosphorylation of hpttg proto-oncogene product. | None |
| the oncogenic effect of increased expression of securin may result from modulation of p53 functions | None |
| Expression of hpttg proto-oncogene in lymphoid neoplasias. | None |
| High expression of the sister-chromatid separation regulator and proto-oncogene hSecurin occurs in a subset of myeloid leukaemias but is not implicated in the pathogenesis of aneuploidy. | None |
| PTTG may induce apoptosis by down-regulation of oncogenes such as v-Jun and v-maf and up-regulation of the histone family of genes. | None |
| Tumor suppressor activity of KLF6 mediated by downregulation of the PTTG1 oncogene. | None |
| PTTG1 oncogene promotes tumor malignancy via epithelial to mesenchymal transition and expansion of cancer stem cell population. | None |
| Results show that a single mutation in pttg1 is sufficient to trigger the oncogenic properties of Securin. The finding of this point mutation in patients might be used as an effective strategy for early detection of cancer. | None |
| Down-regulation of the oncogene PTTG1 via the KLF6 tumor suppressor during induction of myeloid differentiation. | None |