| KLF4 is a tumor suppressor in colorectal cancer. | colorectal, |
| Reduced levels of KLF4 tumor suppressor activity in colon tumors may be driven by elevated beta-catenin/Tcf signaling. | colorectal, |
| Data show that that KLF4 is inactivated by either genetic or epigenetic mechanisms in a large subset of medulloblastomas and that it likely functions as a tumor suppressor gene in the pathogenesis of medulloblastoma. | medulloblastomas, |
| KLF4 is a tumor suppressor in B-cell non-Hodgkin lymphoma and in classic Hodgkin lymphoma. | lymphoma, |
| Expression of the tumor suppressor Kr??ppel-like factor 4 as a prognostic predictor for colon cancer. | colorectal, |
| KLF4 is a novel candidate tumor suppressor gene in pancreatic ductal carcinoma. | pancreatic, |
| Restored expression of KLF4, a putative tumor suppressor, downregulated IFITM3 expression in colon cancer cells in vitro. | colorectal, |
| First functional, in vivo evidence for KLF4 as a tumor suppressor in breast cancer cells. | breast, |
| KLF4 may function as a tumor suppressor in cervical carcinoma by inhibiting cell growth and tumor formation. | cervical, |
| Kruppel-like factor 4, a tumor suppressor in hepatocellular carcinoma cells reverts epithelial mesenchymal transition by suppressing slug expression. | liver, |
| KLF4 is a putative tumor suppressor gene epigenetically silenced in renal cell cancers by promoter CpG methylation and that it has prognostic value for renal cell progression. | kidney, |
| KLF4 functions as a tumor suppressor gene in ovarian cancer cells by inhibiting TGFB-induced epithelial mesenchymal transition. | ovarian, |
| KLF4 might act as a tumor suppressor in esophageal squamous cell carcinoma and the expression status of KLF4 could be considered as a prognosis predictor. | esophageal, |
| Authors show that absence of Klf4 accelerates carcinogenesis and correlates with the absence of cytokeratin 1 expression. Results suggest a potential role for KLF4 as a tumor suppressor gene for the tongue epithelium. | tongue, |
| KLF4 might play Janus-faced roles in oral squamous cell carcinoma, acting both as a tumor suppressor and as an oncogene. | oral |
| Tumor suppressive role of KLF-4 in human endometrial carcinoma tissues. | endometrial, |
| Results showed that lower KLF-4 expression was correlated with malignant colorectal cancer (CRC) status and poor prognosis in CRC patients. Moreover, KLF-4 suppression promoted the proliferation of CRC cells in vitro providing novel insights into the tumor suppressive role of KLF-4 in CRC. | colorectal, |
| Novel tumor-suppressor function of KLF4 in pediatric T-cell acute lymphoblastic leukemia | leukemia,pediatric, |
| Epigenetic silencing of the tumor suppressor genes SPI1, PRDX2, KLF4, DLEC1, and DAPK1 in childhood and adolescent lymphomas | lymphoma, |
| The association between KLF4 as a tumor suppressor and the prognosis of hepatocellular carcinoma after curative resection | liver, |