| Isolation and characterization of a novel oncogene, amplified in liver cancer 1, within a commonly amplified region at 1q21 in hepatocellular carcinoma. | liver, |
| our data strongly support that CHD1L is a novel oncogene and plays an important role in hepatocellular carcinoma pathogenesis | liver, |
| CHD1L is the target oncogene within the 1q21 amplicon and plays a pivotal role in colorectal carcinoma pathogenesis. | colorectal, |
| CHD1L promotes tumor progression and predicts survival in colorectal carcinoma. | colorectal, |
| ALC1 is the target oncogene within the chromosome 1q21 amplicon and plays a pivotal role in hepeatocellular carcinoma pathogenesis. | None |
| CHD1L: a novel oncogene. | None |
| NAD(+)-metabolite and nucleic acid poly-ADP-ribose triggers ALC1 to drive chromatin relaxation. Modular allostery in this oncogene tightly controls its robust, DNA-damage-dependent activation. | None |