Sentence and cancer type
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SentenceCancertype
Suppression of KEAP1 in lung tumor cells resulted in increased expression of PPARgamma and was accompanied by induction of cell differentiation markers andattenuated expression of cancer stem cell markers.lung
Keap1 functions as a suppressor of tumor metastasis by targeting the Nrf2/S100P pathway in NSCLC cells.unknown
Results show up-regulation of TrkB and down-regulation of Runx3 and Keap1 in breast cancer cells and suggest that TrkB plays a key role in tumorigenicity and metastasis of breast cancer cells through suppression of Runx3 or Keap1.breast