| The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset. | skin, |
| studies establish SETDB1 as an oncogene in melanoma and underscore the role of chromatin factors in regulating tumorigenesis | skin, |
| Gene amplification of the histone methyltransferase SETDB1 contributes to human lung tumorigenesis. | lung, |
| SETDB1 is a bona fide oncogene undergoing gene amplification-associated activation in lung cancer. | lung, |
| SETDB1 is an oncogene that is frequently up-regulated in human HCCs; the multiplicity of SETDB1 activating mechanisms at the chromosomal, transcriptional, and posttranscriptional levels together facilitates SETDB1 up-regulation in human HCC | liver, |
| Identify SETDB1 as a prominent oncogene in breast cancer. The c-MYC-BMI1 axis is essential for SETDB1-mediated breast tumourigenesis. | breast, |