Showing 21-22 of 22 items.

Sentence	Cancertype
Soluble E-cadherin: a critical oncogene modulating receptor tyrosine kinases, MAPK and PI3K/Akt/mTOR signaling.	None
Study of transgenic mouse model provides insights into invasive lobular carcinoma (ILC) development by uncovering the direct consequences of E-cadherin inactivation in the mouse mammary gland and reveals actomyosin contractility as a critical barrier to ILC development. The discovery of actomyosin regulation as a druggable oncogenic pathway might provide therapeutic opportunities to treat E-cadherin mutated cancers.	None