Sentences
Showing 101-120 of 159 items.
| PubMed | Sentence | Cancertype | Gene ID |
|---|---|---|---|
| 26013684 | Our work shows that shorter TAp63 isoforms (TAp63beta/gamma) are specifically induced in human keratinocytes and cooperate with Notch signaling to activate transcription of late differentiation genes supporting their role as putative tumor suppressors. | None | 8626 |
| 30106161 | The results indicated that Notch1 and its target genes, Hes family BHLH transcription factor 1 and Hesrelated family BHLH transcription factor with YRPW motif 1, were suppressed by miR34b directly In conclusion, EWSFLI1 may modulate miR34b expression directly or indirectly, and miR34b potentially has an oncogenic role in Ewing_s sarcoma by downregulating Notch1. | sarcoma, | 407041 |
| 10797286 | Expression of an activated Notch4(int-3) oncoprotein disrupts morphogenesis and induces an invasive phenotype in mammary epithelial cells in vitro. | None | 65123 |
| 19050759 | Prdm proto-oncogene transcription factor family expression and interaction with the Notch-Hes pathway in mouse neurogenesis. | None | 59335 |
| 19050759 | Prdm proto-oncogene transcription factor family expression and interaction with the Notch-Hes pathway in mouse neurogenesis. | None | 63977 |
| 15870272 | negative feedback regulation in which Met activation leads to transcriptional induction of Notch function, which in turn limits HGF activity through repression of the Met oncogene | None | 4233 |
| 28790107 | deficiency alters the expression of a crucial subset of TAL1- and NOTCH1-regulated genes, including the MYB and MYC oncogenes, respectively. | None | 4602 |
| 18974129 | Identification of Pbx1, a potential oncogene, as a Notch3 target gene in ovarian cancer. | ovarian, | 5087 |
| 12539049 | cloning and functional analyses of the t(11;19) fusion oncogene: t(11;19)(q21;p13) translocation in mucoepidermoid carcinoma creates a novel fusion product that disrupts a Notch signaling pathway. | None | 23373 |
| 19050759 | Prdm proto-oncogene transcription factor family expression and interaction with the Notch-Hes pathway in mouse neurogenesis. | None | 56980 |
| 25808869 | Manic fringe promotes a claudin-low breast cancer phenotype through notch-mediated PIK3CG induction. | breast, | 4242 |
| 25808869 | Mfng is an oncogene acting through Notch-mediated induction of Pik3cg. | None | 4242 |
| 19050759 | Prdm proto-oncogene transcription factor family expression and interaction with the Notch-Hes pathway in mouse neurogenesis. | None | 63978 |
| 30931528 | Results show that Notch signalling exerts opposing effects in oncogenic Kras-induced MPN; it functions as a potent oncogene in leukaemia cells per se (Kong et al , 2019), but acts as a tumour suppressor gene in non-haematopoietic cells. | None | 3845 |
| 24216479 | Isoprenylcysteine carboxylmethyltransferase deficiency exacerbates KRAS-driven pancreatic neoplasia via Notch suppression. | pancreatic, | 3845 |
| 20484026 | Authors used a mouse model in which an oncogenic allele of K-ras is activated and Notch1 is deleted in the pancreas. Loss of Notch1 in this model resulted in increased tumor incidence implying that Notch1 functions as a tumor suppressor gene in PDAC. | None | 3845 |
| 30931528 | Results show that Notch signalling exerts opposing effects in oncogenic Kras-induced MPN; it functions as a potent oncogene in leukaemia cells per se (Kong et al , 2019), but acts as a tumour suppressor gene in non-haematopoietic cells. | None | 3845 |
| 19050759 | Prdm proto-oncogene transcription factor family expression and interaction with the Notch-Hes pathway in mouse neurogenesis. | None | 56979 |
| 19050759 | Prdm proto-oncogene transcription factor family expression and interaction with the Notch-Hes pathway in mouse neurogenesis. | None | 63976 |
| 12539049 | cloning and functional analyses of the t(11;19) fusion oncogene t(11;19)(q21;p13) translocation in mucoepidermoid carcinoma creates a novel fusion product that disrupts a Notch signaling pathway. | None | 84441 |