Sentences
Showing 121-140 of 159 items.
| PubMed | Sentence | Cancertype | Gene ID |
|---|---|---|---|
| 17114293 | NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth. | leukemia, | 4609 |
| 18765521 | Oncogenic NOTCH1 control of MYC and PI3K: challenges and opportunities for anti-NOTCH1 therapy in T-cell acute lymphoblastic leukemias and lymphomas. | lymphoma,leukemia, | 4609 |
| 17114293 | identify c-MYC as an essential mediator of NOTCH1 signaling and integrate NOTCH1 activation with oncogenic signaling pathways upstream of c-MYC | None | 4609 |
| 18471881 | Cooperation of Gata3, c-Myc and Notch in malignant transformation of double positive thymocytes. | None | 4609 |
| 28790107 | deficiency alters the expression of a crucial subset of TAL1- and NOTCH1-regulated genes, including the MYB and MYC oncogenes, respectively. | None | 4609 |
| 19050759 | Prdm proto-oncogene transcription factor family expression and interaction with the Notch-Hes pathway in mouse neurogenesis. | None | 59336 |
| 21670468 | Data show that thymic expression of the Tal1 and Lmo2 oncogenes results in rapid development of T-ALL, and similar to T-ALL patients, more than half the leukemic mice develop spontaneous mutations in Notch1. | leukemia, | 4005 |
| 19050759 | Prdm proto-oncogene transcription factor family expression and interaction with the Notch-Hes pathway in mouse neurogenesis. | None | 56978 |
| 21670468 | Data show that thymic expression of the Tal1 and Lmo2 oncogenes results in rapid development of T-ALL, and similar to T-ALL patients, more than half the leukemic mice develop spontaneous mutations in Notch1. | leukemia, | 6886 |
| 20190740 | Genome-wide RNA-mediated interference screen identifies miR-19 targets in Notch-induced T-cell acute lymphoblastic leukaemia. | None | 406979 |
| 23307033 | The viral oncogene Np9 acts as a critical molecular switch for co-activating beta-catenin, ERK, Akt and Notch1 and promoting the growth of human leukemia stem/progenitor cells. | leukemia, | 207 |
| 25344626 | Data suggest that expression, processing, and activation of (that is, signal transduction via) Notch1 (neurogenic locus notch homolog protein 1), Pten (phosphatase and tensin homolog), and Akt1 (thymoma viral proto-oncogene 1) are involved in oogenesis; oogenesis proceeds via both recruitment of primordial follicles and proliferation of granulosa cells. | thymoma, | 207 |
| 23998804 | High iodine blocks a Notch/miR-19 loop activated by the BRAF(V600E) oncoprotein and restores the response to TGFbeta in thyroid follicular cells. | thyroid, | 673 |
| 21052088 | inhibition of two oncogenic pathways (AURKA and NOTCH-1) by small-molecular inhibitors induced significant growth arrest in NK-cell lines | None | 6790 |
| 18765521 | Oncogenic NOTCH1 control of MYC and PI3K: challenges and opportunities for anti-NOTCH1 therapy in T-cell acute lymphoblastic leukemias and lymphomas. | lymphoma,leukemia, | 5290 |
| 25043004 | Loss of oncogenic Notch1 with resistance to a PI3K inhibitor in T-cell leukaemia. | None | 5290 |
| 19050759 | Prdm proto-oncogene transcription factor family expression and interaction with the Notch-Hes pathway in mouse neurogenesis. | None | 93166 |
| 27666896 | our results show for the first time that miR-101 acts as a tumor suppressor in T-cell acute lymphoblastic leukaemia and it could enhance chemotherapeutic sensitivity. Furthermore, Notch1 was identified to be a novel target of miR-101. This study indicates that miR-101 may represent a potential therapeutic target for T-cell acute lymphoblastic leukemia intervention. | leukemia, | 406893 |
| 28941308 | The demonstration that miR-124 inhibits gastric cancer cell growth supports the concept that miR-124 functions as a tumor suppressor by a mechanism that involves translational repression of the JAG1 and the inhibition of Notch signaling pathway. | gastric, | 406908 |
| 23314443 | FAM172A may be a novel tumor-suppressor gene that plays an important role in cell cycle mediated, at least partially, by the Notch 3 signaling pathway. | None | 83989 |