Sentences
Showing 141-159 of 159 items.
| PubMed | Sentence | Cancertype | Gene ID |
|---|---|---|---|
| 33148199 | The DLC-1 tumor suppressor is involved in regulating immunomodulation of human mesenchymal stromal /stem cells through interacting with the Notch1 protein | None | 9940 |
| 21427293 | Functional interactions between Lmo2, the Arf tumor suppressor, and Notch1 in murine T-cell malignancies. | None | 1029 |
| 25494473 | miR-181c can be considered a valuable indicator for the outcome of glioblastoma multiforme patients. miR-181c acts as a tumor suppressor that attenuates proliferation, invasion, and self-renewal capacities by downregulation of Notch2 in glioma cells. | glioblastoma,glioma, | 406957 |
| 27460529 | Niclosamide inhibits colon cancer progression through downregulation of the Notch pathway and upregulation of the tumor suppressor miR-200 family | colorectal, | 406983 |
| 30335900 | Results found the expression levels of NCOA5 mRNA and protein significantly decreased in cervical cancer (CC) tissues and correlated with poor overall survival. Its upregulation might suppress cancer cell proliferation, migration, and invasion by inactivating NOTCH3 signaling pathway. These findings suggest that NCOA5 acts as a tumor suppressor and represents a potential novel prognostic marker for overall survival in CC. | cervical, | 57727 |
| 20847082 | NEURL1 expression was downregulated in medulloblastoma compared to normal cerebellar tissue with lowest expression levels in hedgehog-activated tumors; conclude NEURL1 is candidate tumor suppressor in MB at least in part through effects on Notch pathway | None | 9148 |
| 21435444 | in the mammalian skin, IKK1 functions as a differentiation regulator and tumor suppressor through the Notch signaling path | skin, | 1147 |
| 27335110 | Tumor Suppressor HIPK2 Regulates Malignant Growth via Phosphorylation of Notch1 | None | 28996 |
| 24838835 | Our data provides evidence on FBXW7 as a critical tumor suppressor mutated and inactivated in melanoma that results in sustained NOTCH1 activation and renders NOTCH signaling inhibition as a promising therapeutic strategy in this setting. | skin, | 55294 |
| 28941308 | The demonstration that miR-124 inhibits gastric cancer cell growth supports the concept that miR-124 functions as a tumor suppressor by a mechanism that involves translational repression of the JAG1 and the inhibition of Notch signaling pathway. | gastric, | 406909 |
| 19479935 | Defects in Notch-1 signaling may play a role in human prostate tumor formation in part via a mechanism that involves regulation of the PTEN tumor suppressor gene. | prostate, | 5728 |
| 16096376 | Notch homolog 1 can participate in cross-talk with other signaling pathways such as Ras/Raf/MEK/ERK through the regulation of the PTEN tumor suppressor | None | 5728 |
| 26853560 | RBM10 is a tumor suppressor that represses Notch signaling and cell proliferation through the regulation of NUMB alternative splicing | None | 8241 |
| 27229929 | Systematic interactome mapping of acute lymphoblastic leukemia cancer gene products reveals EXT-1 tumor suppressor as a Notch1 and FBWX7 common interactor | leukemia, | 2131 |
| 21464222 | Repression of tumor suppressor miR-451 is essential for NOTCH1-induced oncogenesis in T-ALL. | None | 574411 |
| 28017968 | Mutations in NOTCH1 PEST domain orchestrate CCL19-driven homing of chronic lymphocytic leukemia cells by modulating the tumor suppressor gene DUSP22 | leukemia, | 56940 |
| 28082020 | research suggests that miR424-5p may act as a novel anti-oncogene in cervical cancer by blocking cell growth through targeting KDM5B-Notch pathway | cervical, | 494336 |
| 28941308 | The demonstration that miR-124 inhibits gastric cancer cell growth supports the concept that miR-124 functions as a tumor suppressor by a mechanism that involves translational repression of the JAG1 and the inhibition of Notch signaling pathway. | gastric, | 406907 |
| 29581534 | Further studies verified that miR-1 regulates EMT signalling pathways directly through Notch2. Therefore, these results confirm that, as a tumor suppressor gene, miR-1 may be a potential tumor marker for the early diagnosis of esophageal squamous cell carcinoma and a new drug target. | esophageal, | 406904 |